4-Chloropyrrolo[2,3-d]pyrimidine (CAS No. 3680-69-1) is a high-purity fused heterocyclic compound widely used as an important pharmaceutical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and biologically active molecules. The reactive chlorine atom at the 4-position enables efficient nucleophilic substitution reactions, making this compound a valuable building block for the preparation of kinase inhibitors, nucleoside analogues, antiviral agents, and oncology drug candidates. It is extensively employed in medicinal chemistry, pharmaceutical process development, and custom synthesis projects. Hestur Pharma, Hyderabad, India, manufactures and supplies premium-quality 4-Chloropyrrolo[2,3-d]pyrimidine with consistent purity and excellent batch-to-batch quality for pharmaceutical companies, CROs, CDMOs, research organizations, and specialty chemical manufacturers. Our product is suitable for laboratory research, pilot-scale production, and commercial manufacturing. We offer flexible packaging, competitive pricing, comprehensive documentation including Certificate of Analysis (COA) and Safety Data Sheet (SDS), and dependable domestic and international supply. Hestur Pharma is committed to delivering high-quality pharmaceutical intermediates and custom synthesis solutions that meet global industry standards.
| Pack Size | Stock | Price (₹) | Quantity | Delivery Time | Action |
|---|---|---|---|---|---|
| 5g | 10 |
₹2,126
₹2,126
|
1
|
5–7 Business Days |
|
| 25g | 10 |
₹3,560
₹3,560
|
1
|
5–7 Business Days |
|
| 100g | 10 |
₹5,896
₹5,896
|
1
|
5–7 Business Days |
|
| 250g | 5 |
₹10,750
₹10,750
|
1
|
5–7 Business Days |
|
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| Category | API Intermediate |
| Chemical Name | 4-Chloropyrrolo[2,3-d]pyrimidine |
| CAS No. | 3680-69-1 |
| Synonyms | 4-Chloropyrrolo[2,3-d]pyrimidine, 4-Chloro-7-deazapurine, 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine |
| Chemical Formula | C₆H₄ClN₃ |
| Molecular Weight | 153.57 g/mol g/mol |
| Applications | 4-Chloropyrrolo[2,3-d]pyrimidine (CAS No. 3680-69-1) is a versatile pharmaceutical intermediate widely used in the synthesis of kinase inhibitor APIs. It is a key building block for drugs such as Tofacitinib, Ruxolitinib, Baricitinib, Capivasertib, Pacritinib, Peficitinib, Oclacitinib, Vibegron, Ivarmacitinib, Itacitinib, Tinengotinib, Abrocitinib, Delgocitinib, and Ritlecitinib. It is extensively used in the development of treatments for cancer, autoimmune, inflammatory, and dermatological diseases. |
| Test | Specification |
|---|---|
| Appearance | White to Off-White Crystalline Powder |
| Purity by HPLC | ≥98.0% |
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